NIMH Chemical Synthesis and Drug Supply Program

Compound Information Page

NIMH Code: A-502A
Compound Name: Adapiperazine dihydrochloride
Alternative Name: 10-[3-(4-Adamantan-2-ylpiperazin-1-yl)propyl]-2-chloro-10H-phenothiazine Dihydrochloride
PubChemID: 62872
CAS: 57942-72-0
Molecular Formula: C29H38Cl3N3S
Biological Activity: Dopamine receptor antagonist, antiemetic, antipsychotic agent
References: Klimova, N.V.; Lavrova, L.N.; Pushkar, G.V.; Shar'yan, M.I.; Arendaruk, A.P.; Skoldinov, A.P.; Khimiko-Farm. Z., 1975, 9, 8-11. Kovalev, I.E.; Durakova, L.I.; Kovaleva, V.L.; Shmar'ian, M.I.; Klimova, N.V. Farmakol Toksikol, 1977, 40, 573-578.
Comments: PubChem ID is for the base
Last Updated 2021-02-16 09:08 AM
Structure of A-502A
About The Program

Since 1959, the NIMH Chemical Synthesis and Drug Supply Program has synthesized and distributed novel research chemicals, psychoactive drugs, and compounds that are unavailable from commercial sources to the scientific community working on research relevant to mental health.

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