NIMH Chemical Synthesis and Drug Supply Program

Compound Information Page

NIMH Code: R-905
Compound Name: N-(2-Aminoethyl)-5-(3-fluorophenyl)-4-thiazole carboxamide hydrochloride
Alternative Name: 5-methyl-2,5,19-triazatetracyclo[13.4.0.02,7.08,13]nonadeca-1(15),8,10,12,16,18-hexaene;hydrochloride
Abbreviation: Mirtazapine hydrochloride; Ro 41-1049 hydrochloride
PubChemID: 11695149
CAS: 207516-99-2
Molecular Formula: C12H13ClFN3OS
Biological Activity: Serotonin 5-HT2, 5-HT3, and histamine 1 H1 receptor antagonist used an atypical antidepressant
References: Anttila, S.A.; Leinonen, E.V., CNS Drug Rev., 2001, 7, 249-264. Watanabe, N.; Omori, I.M.; Nakagawa, A.; Cipriani, A.; Barbui, C.; Churchill, R.; Furukawa, T.A., Cochrane Database Syst. Rev., 2011, 12, CD006528.
Comments:
Last Updated 2021-04-09 03:13 PM
Structure of R-905
About The Program

Since 1959, the NIMH Chemical Synthesis and Drug Supply Program has synthesized and distributed novel research chemicals, psychoactive drugs, and compounds that are unavailable from commercial sources to the scientific community working on research relevant to mental health.

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