NIMH Code: | P-908 |
Compound Name: | 11-(1-Piperazinyl)-5H-dibenzo[b,e][1,4]diazepine (C21) Dihydrochloride New! |
Alternative Name: | DREADD Compound 21 Dihydrochloride |
Abbreviation: | C21 2HCl |
PubChemID: | 11818276 (base) |
CAS: | 56296-18-5 (base) |
Molecular Formula: | C17H20Cl2N4 |
Biological Activity: | DREADD ligand |
References: | 1. Thompson, K. J.; Khajehali, E.; Bradley, S. J.; Navarrete, J. S.; Huang, X. P.; Slocum, S.; Jin, J.; Liu, J.; Xiong, Y.; Olsen, R. H. J.; Diberto, J. F.; Boyt, K. M.; Pina, M. M.; Pati, D.; Molloy, C.; Bundgaard, C.; Sexton, P. M.; Kash, T. L.; Krashes, M. J.; Christopoulos, A.; Roth, B. L.; Tobin, A. B. ACS Pharmacol. Transl. Sci. 2018, 1, 61-72. 2. Jendryka, M.; Palchaudhuri, M.; Ursu, D.; van der Veen, B.; Liss, B.; Katzel, D.; Nissen, W.; Pekcec, A., Sci. Rep. 2019, 9, 4522. |
Comments: | Water soluble |
Last Updated 2021-05-28 11:42 AM |
Since 1959, the NIMH Chemical Synthesis and Drug Supply Program has synthesized and distributed novel research chemicals, psychoactive drugs, and compounds that are unavailable from commercial sources to the scientific community working on research relevant to mental health.