NIMH Chemical Synthesis and Drug Supply Program

Compound Information Page

Compound Name: 11-(1-Piperazinyl)-5H-dibenzo[b,e][1,4]diazepine (C21) Dihydrochloride New!
NIMH Code: P-908
Alternative Name: DREADD Compound 21 Dihydrochloride
Abbreviation: C21 2HCl
Indications: DREADD ligand
Package Sizes:
References: 1. Thompson, K. J.; Khajehali, E.; Bradley, S. J.; Navarrete, J. S.; Huang, X. P.; Slocum, S.; Jin, J.; Liu, J.; Xiong, Y.; Olsen, R. H. J.; Diberto, J. F.; Boyt, K. M.; Pina, M. M.; Pati, D.; Molloy, C.; Bundgaard, C.; Sexton, P. M.; Kash, T. L.; Krashes, M. J.; Christopoulos, A.; Roth, B. L.; Tobin, A. B. ACS Pharmacol. Transl. Sci. 2018, 1, 61-72. 2. Jendryka, M.; Palchaudhuri, M.; Ursu, D.; van der Veen, B.; Liss, B.; Katzel, D.; Nissen, W.; Pekcec, A., Sci. Rep. 2019, 9, 4522.
CAS: 56296-18-5 (base)
Molecular Formula: C17H20Cl2N4
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HBD:
RotB:
PubChemID: 11818276 (base)
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Comments: Water soluble
Last Updated 2020-09-10 03:00 PM
Structure of P-908
About The Program

Since 1959, the NIMH Chemical Synthesis and Drug Supply Program has synthesized and distributed novel research chemicals, psychoactive drugs, and compounds that are unavailable from commercial sources to the scientific community working on research relevant to mental health.

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