NIMH Chemical Synthesis and Drug Supply Program

Compound Information Page

Structure of A-801
Compound Name: (RS)-1-Aminoindan-1,5-dicarboxylic Acid
NIMH Code: A-801
Alternative Name:
Abbreviation: AIDA, UPF 523
Indications: selective group I metabotropic glutamate receptor antagonist
Package Sizes:
References: P. Gubellini, A. Pisani, D. Cettonze, G. Bernardi and P. Calabresi, Metabotropic glutamate receptors and striatal synaptic plasticity: implications for neurological diseases, Prog. Neurobiol., 74, 271-300 (2004); F. Moroni, G. Lombardi, C. Thomsen, P. Leonardi, S. Attucci, F. Peruginelli, S. A. Torregrossa, D. E. Pellegrini-Giampietro, R. Luneia and R. Pellicciari, Pharmacological characterization of 1-aminoindan-1,5-dicarboxylic acid, a potent mGluR1 antagonist, J. Pharmacol. Exp. Ther., 281, 721-729 (1997).
CAS: 168560-79-0
Molecular Formula: C11H11NO4
HBA: 5
HBD: 3
RotB: 2
PubChemID: 2071
AlogP: -1.7063034
TPSA: 100.62
Activity: Excitatory Amino Acid Antagonist
Comments:
Last Updated 2008-11-10 03:09 PM