NIMH Chemical Synthesis and Drug Supply Program
Compound Information Page
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| Compound Name: | (RS)-1-Amino-5-phosphonoindan-1-carboxylic Acid |
| NIMH Code: | A-803 |
| Alternative Name: | |
| Abbreviation: | (RS)-APICA |
| Indications: | Rigid MPPG analog; selective group II metabotropic glutamate receptor antagonist |
| Package Sizes: | |
| References: | E. Viard and H. N. Sapru, Cardiovascular responses to activation of metabotropic glutamate receptors in the nTS of the rat, Brain Res., 952, 308-321 (2002); D. Ma, H. Tian, H. Sun, A. P. Kozikowshi, S. Pshenichkin and J. T. Wroblewski, Synthesis and biological activity of cyclic analogues of MPPG and MCPG as metabotropic glutamate receptor antagonists, Bioorg. Med. Chem. Lett., 7, 1195-1198 (1997). |
| CAS: | |
| Molecular Formula: | C10H12NO5P |
| HBA: | 6 |
| HBD: | 4 |
| RotB: | 2 |
| PubChemID: | 4694355 |
| AlogP: | -2.4794362 |
| TPSA: | 130.66 |
| Activity: | |
| Comments: | |
| Last Updated 2008-11-10 03:12 PM | |