NIMH Chemical Synthesis and Drug Supply Program

Compound Information Page

Structure of B-504
Compound Name: N-Methyl-N-(1-methyl-4-pyrrolidino-2-butynyl)acetamide Oxalate
NIMH Code: B-504
Alternative Name:
Abbreviation: BM-5 Oxalate
Indications: muscarinic partial agonist (oxotremorine analog)
Package Sizes:
References: B. Resul, R. Dahlbom, B. Ringdahl and D. J. Jenden, N-Alkyl-N-(4-tert-amino-1-methyl-2-butynyl)carboxamides, a new class of potent oxotremorine antagonists, Eur. J. Med. Chem.-Chim. Ther., 17, 317-322 (1982); O. Nordstrom, P. Alberts, A. Westlind, A. Unden and T. Bartfai, Presynaptic antagonist-postsynaptic agonist at muscarinic cholinergic synapses: N-methyl-N-(1-methyl-4-pyrrolidino-2-butynyl)acetamide, Mol. Pharmacol., 24, 1-5 (1983).
CAS: 83481-69-0
Molecular Formula: C14H22N2O5
HBA: 2
HBD: 0
RotB: 4
PubChemID: 55005
AlogP: .4807
TPSA: 23.55
Activity: Muscarinic partial agonist
Comments:
Last Updated 2008-11-11 02:23 PM