NIMH Chemical Synthesis and Drug Supply Program

Compound Information Page

Structure of S-704
Compound Name: (±)-1-(4'-Aminophenyl)-7-bromo-8-methoxy-3-methyl-2,3,4,5-tetrahydro-(1H)-3-benzazepine
NIMH Code: S-704
Alternative Name: 4'-Amino-8-O-methyl-SKF-83566
Abbreviation:
Indications: precursor to dopamine D1 receptor alkylating ligand (antagonist)
Package Sizes:
References: V. Bakthavachalam, N. Baindur, B. K. Madras and J. L. Neumeyer, Fluorescent probes for dopamine receptors: synthesis and characterization of fluorescein and 7-nitrobenz-2-oxa-1,3-diazol-4-yl conjugates of D-1 and D-2 receptor ligands, J. Med. Chem., 34, 3235-3241 (1991)
CAS:
Molecular Formula: C18H21BrN2O
HBA: 3
HBD: 1
RotB: 2
PubChemID:
AlogP: 3.5428
TPSA: 38.49
Activity:
Comments:
Last Updated 2008-11-11 03:00 PM