NIMH Code: | J-905 |
Compound Name: | 8-Chloro-11-(4-ethylpiperazin-1-yl)-2-fluoro-5H-dibenzo[b,e][1,4]diazepine dihydrochloride (JHU37107 dihydrochloride) |
Alternative Name: | JHU37107 dihydrochloride |
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Molecular Formula: | C19H22Cl3FN4 |
Biological Activity: | DREADD agonist with high affinity and potency for CNS applications. |
References: | DREADD Actuators. PCT application 1,916,892. Bonaventura, J.; Eldridge, M. A. G.; Hu, F.; et al. High-potency ligands for DREADD imaging and activation in rodents and monkeys. Nat. Commun. 2019, 10, 4627. |
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Last Updated 2023-11-17 03:33 PM |
Since 1959, the NIMH Chemical Synthesis and Drug Supply Program has synthesized and distributed novel research chemicals, psychoactive drugs, and compounds that are unavailable from commercial sources to the scientific community working on research relevant to mental health.