NIMH Chemical Synthesis and Drug Supply Program

Compound Information Page

Compound Name: (RS)-1-Aminoindan-1,5-dicarboxylic Acid
NIMH Code: A-801
Alternative Name:
Abbreviation: AIDA, UPF 523
Indications: selective group I metabotropic glutamate receptor antagonist
Package Sizes:
References: P. Gubellini, A. Pisani, D. Cettonze, G. Bernardi and P. Calabresi, Metabotropic glutamate receptors and striatal synaptic plasticity: implications for neurological diseases, Prog. Neurobiol., 74, 271-300 (2004); F. Moroni, G. Lombardi, C. Thomsen, P. Leonardi, S. Attucci, F. Peruginelli, S. A. Torregrossa, D. E. Pellegrini-Giampietro, R. Luneia and R. Pellicciari, Pharmacological characterization of 1-aminoindan-1,5-dicarboxylic acid, a potent mGluR1 antagonist, J. Pharmacol. Exp. Ther., 281, 721-729 (1997).
CAS: 168560-79-0
Molecular Formula: C11H11NO4
HBA: 5
HBD: 3
RotB: 2
PubChemID: 2071
AlogP: -1.7063034
TPSA: 100.62
Activity: Excitatory Amino Acid Antagonist
Last Updated 2008-11-10 03:09 PM
Structure of A-801
About The Program

Since 1959, the NIMH Chemical Synthesis and Drug Supply Program has synthesized and distributed novel research chemicals, psychoactive drugs, and compounds that are unavailable from commercial sources to the scientific community working on research relevant to mental health.

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