NIMH Chemical Synthesis and Drug Supply Program

Compound Information Page

NIMH Code: A-803
Compound Name: (RS)-1-Amino-5-phosphonoindan-1-carboxylic acid
Alternative Name:
Abbreviation: (RS)-APICA
PubChemID: 4694355
CAS: 170847-18-4
Molecular Formula: C10H12NO5P
Biological Activity: Rigid MPPG analog; selective group II metabotropic glutamate receptor antagonist
References: Viard, E.; Sapru, H.N. Brain Res., 2002, 952, 308-321. Ma, D.; Tian, H.; Sun, H.; Kozikowshi, A. P. ; Pshenichkin, S.; Wroblewski, J. T. . Bioorg. Med. Chem. Lett., 1997, 7, 1195-1198.
Last Updated 2021-02-16 09:54 AM
Structure of A-803
About The Program

Since 1959, the NIMH Chemical Synthesis and Drug Supply Program has synthesized and distributed novel research chemicals, psychoactive drugs, and compounds that are unavailable from commercial sources to the scientific community working on research relevant to mental health.

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