NIMH Chemical Synthesis and Drug Supply Program

Compound Information Page

Compound Name: N-Methyl-N-(1-methyl-4-pyrrolidino-2-butynyl)acetamide Oxalate
NIMH Code: B-504
Alternative Name:
Abbreviation: BM-5 Oxalate
Indications: muscarinic partial agonist (oxotremorine analog)
Package Sizes:
References: B. Resul, R. Dahlbom, B. Ringdahl and D. J. Jenden, N-Alkyl-N-(4-tert-amino-1-methyl-2-butynyl)carboxamides, a new class of potent oxotremorine antagonists, Eur. J. Med. Chem.-Chim. Ther., 17, 317-322 (1982); O. Nordstrom, P. Alberts, A. Westlind, A. Unden and T. Bartfai, Presynaptic antagonist-postsynaptic agonist at muscarinic cholinergic synapses: N-methyl-N-(1-methyl-4-pyrrolidino-2-butynyl)acetamide, Mol. Pharmacol., 24, 1-5 (1983).
CAS: 83481-69-0
Molecular Formula: C14H22N2O5
HBA: 2
HBD: 0
RotB: 4
PubChemID: 55005
AlogP: .4807
TPSA: 23.55
Activity: Muscarinic partial agonist
Last Updated 2008-11-11 02:23 PM
Structure of B-504
About The Program

Since 1959, the NIMH Chemical Synthesis and Drug Supply Program has synthesized and distributed novel research chemicals, psychoactive drugs, and compounds that are unavailable from commercial sources to the scientific community working on research relevant to mental health.

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