NIMH Chemical Synthesis and Drug Supply Program

Compound Information Page

NIMH Code: B-139
Compound Name: (E)-7-Benzylidene-7-dehydronaltrexone hydrochloride
Alternative Name:
Abbreviation: BNTX hydrochloride
PubChemID: 5310988
CAS: 173556-52-0
Molecular Formula: C27H28ClNO4
Biological Activity: selective non-peptide delta1 opioid receptor antagonist
References: Ohkawa, S.; Portoghese, P. S. , J. Med. Chem., 1998, 41, 4177-4180. Miyata, Y; Fujii, H.; Uenohara, Y.; Kobayashi, S. Takeuchi, T.; Nagase, H. Bioorg. Med. Chem. Lett., 2012, 22, 5174-5176.
Comments: Schedule II controlled substance. PubChem ID is for the base.
Last Updated 2021-02-16 03:42 PM
Structure of B-139
About The Program

Since 1959, the NIMH Chemical Synthesis and Drug Supply Program has synthesized and distributed novel research chemicals, psychoactive drugs, and compounds that are unavailable from commercial sources to the scientific community working on research relevant to mental health.

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