NIMH Chemical Synthesis and Drug Supply Program

Compound Information Page

Compound Name: N-[1-(2-Benzo[b]thiophenyl)cyclohexyl]piperidine Hydrochloride
NIMH Code: B-701
Alternative Name:
Abbreviation: BTCP Hydrochloride
Indications: Potent & selective dopamine uptake inhibitor with little affinity for PCP sites
Package Sizes:
References: J. Vignon, V. Pinet, C. Cerruti, J.-M. Kamenka and R. Chicheportiche, [3H]N-[1-(2-Benzo[b]thiophenyl)cyclohexyl]piperidine ([3H]BTCP): a new phencyclidine analog selective for the dopamine uptake complex, Eur. J. Pharmacol., 148, 427-436 (1988); W. Koek, F. C. Colpaert, J. H. Woods and J.-M. Kamenka, The phencyclidine (PCP) analog N-[1-(2-benzo[b]thiophenyl)cyclohexyl]piperidine shares cocaine-like but not other characteristic behavioral effects with PCP, ketamine and MK-801, J. Pharmacol. Exp. Ther., 250, 1019-1027 (1989).
CAS: 112726-66-6
Molecular Formula: C19H26ClNS
HBA: 2
HBD: 0
RotB: 2
PubChemID: 123692
AlogP: 4.8752
TPSA: 31.48
Activity: Dopamine Agonist
Comments:
Last Updated 2008-11-10 03:39 PM
Structure of B-701
About The Program

Since 1959, the NIMH Chemical Synthesis and Drug Supply Program has synthesized and distributed novel research chemicals, psychoactive drugs, and compounds that are unavailable from commercial sources to the scientific community working on research relevant to mental health.

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