NIMH Chemical Synthesis and Drug Supply Program

Compound Information Page

Compound Name: CGS 19755
NIMH Code: C-105
Alternative Name: cis-4-(Phosphonomethyl)piperidine-2-carboxylic Acid
Abbreviation: CGS 19755
Indications: competitive NMDA receptor antagonist; anticonvulsant and anti-ischemic
Package Sizes:
References: A. J. Hutchinson, M. Williams, C. Angst, R. de Jesus, L. Blanchard, R. H. Jackson, E. J. Wilusz, D. E. Murphy, P. S. Bernard, J. Schneider, T. Campbell, W. Guida and M. A. Sills, 4-(Phosphonoalkyl)- and 4-(phosphonoalkenyl)-2-piperidinecarboxylic acids: synthesis, activity at N-methyl-D-aspartic acid receptors, and anticonvulsant activity, J. Med. Chem., 32, 2171-2178 (1989).
CAS: 110347-85-8
Molecular Formula: C7H14NO5P
HBA: 6
HBD: 4
RotB: 3
PubChemID: 68736
AlogP: -3.558853
TPSA: 116.67
Activity: Excitatory Amino Acid Antagonist
Last Updated 2008-11-11 02:25 PM
Structure of C-105
About The Program

Since 1959, the NIMH Chemical Synthesis and Drug Supply Program has synthesized and distributed novel research chemicals, psychoactive drugs, and compounds that are unavailable from commercial sources to the scientific community working on research relevant to mental health.

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