NIMH Chemical Synthesis and Drug Supply Program

Compound Information Page

NIMH Code: C-518
Compound Name: 7-Hydroxychlorpromazine hydrochloride
Alternative Name: 2-Chloro-10-(3-dimethylaminopropyl)-7-hydroxyphenothiazine hydrochloride
Abbreviation: 8-chloro-10-[3-(dimethylamino)propyl]phenothiazin-3-ol hydrochloride
PubChemID: 131668055
CAS: 51938-11-5
Molecular Formula: C17H20Cl2N2OS
Biological Activity: Antiemetic; antipsychotic agent; dopamine antagonist
References: Nodiff, E. A. ; Ina, S.; Oda, N.; Hayazaki, T.; Nishibe, S.; Kohno, T.; Hausman, M.; Manian, A. A., J. Heterocyclic Chem., 1967, 4, 239-245. Yamamura, H. I. ; Manian, A. A.; Snyder, S. H., Life Sci., 1976, 7, 685-691.
Last Updated 2021-02-17 01:09 PM
Structure of C-518
About The Program

Since 1959, the NIMH Chemical Synthesis and Drug Supply Program has synthesized and distributed novel research chemicals, psychoactive drugs, and compounds that are unavailable from commercial sources to the scientific community working on research relevant to mental health.

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