NIMH Chemical Synthesis and Drug Supply Program

Compound Information Page

Compound Name: (RS)-2-Chloro-5 hydroxyphenylglycine
NIMH Code: C-802
Alternative Name: 2-amino-2-(2-chloro-5-hydroxyphenyl)acetic acid
Abbreviation: CHPG
Indications: Metabotropic glutamate mGlu5 receptor agonist
Package Sizes:
References: Gubellini, P.; Pisani, A.; Cettonze, D.; Bernardi, G.; Calabresi, P., Prog. Neurobiol., 2004, 74, 271-300. Neugebauer, V., Pain, 2002, 98, 1-8.
CAS: 170846-74-9
Molecular Formula: C8H8ClNO3
HBA: 5
HBD: 3
RotB: 2
PubChemID: 3645780
AlogP: -1.1620617
TPSA: 83.55
Activity: Metabotropic glutamate mGlu5 receptor agonist
Comments: Available as free acid or sodium salt. CAS Number and PubChem ID are for free acid. CAS Number for sodium salt is 1303993-73-8, PubChem ID 52974246.
Last Updated 2021-02-17 02:27 PM
Structure of C-802
About The Program

Since 1959, the NIMH Chemical Synthesis and Drug Supply Program has synthesized and distributed novel research chemicals, psychoactive drugs, and compounds that are unavailable from commercial sources to the scientific community working on research relevant to mental health.

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