NIMH Chemical Synthesis and Drug Supply Program

Compound Information Page

Compound Name: (-)-2-beta-Carbomethoxy-3-beta-(4-iodophenyl)tropane D-Tartrate
NIMH Code: C-148
Alternative Name:
Abbreviation: beta-CIT, RTI-55
Indications: Dopamine transporter radio-labeled ligand reference standard
Package Sizes:
References: F. I. Carroll, Y. Gao, M. A. Rahman, P. Abraham, K. Parham, A. H. Lewin, J. W. Boja and M. J. Kuhar, Synthesis, ligand binding, QSAR, and CoMFA study of 3-beta-(p-substituted phenyl)tropane-2-beta-carboxylic acid methyl esters, J. Med. Chem., 34, 2719-2725 (1991); I. M. Skogseid, R. Gerdts, R. Nyberg-Hansen, K. Rootwelt and S. J. Bakke, Usefulness of SPECT and MRI in the diagnosis of atypical parkinsonism, Tidsskr. Nor. Laegeforen., 121, 3399-3403 (2001).
CAS: 133647-95-7 (base)
Molecular Formula: C20H26INO8
HBA: 2
HBD: 0
RotB: 3
PubChemID: 108220
AlogP: 3.39
TPSA: 29.54
Activity: Dopamine transporter ligand
Comments:
Last Updated 2014-03-07 04:52 PM
Structure of C-148
About The Program

Since 1959, the NIMH Chemical Synthesis and Drug Supply Program has synthesized and distributed novel research chemicals, psychoactive drugs, and compounds that are unavailable from commercial sources to the scientific community working on research relevant to mental health.

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