NIMH Chemical Synthesis and Drug Supply Program

Compound Information Page

Compound Name: (RS)-alpha-Cyclopropyl-4-phosphonophenylglycine
NIMH Code: C-804
Alternative Name:
Abbreviation: CPPG
Indications: potent group III mGlu antagonist
Package Sizes:
References: J. Klausnitzer, A. Kulla and D. Manahan-Vaughan, Role of the group III metabotropic glutamate receptor in LTP, depotentiation and LTD in the dentate gyrus of freely moving rats, Neuropharmacology, 46, 160-170 (2004); V. Neugebauer, Metabotropic glutamate receptors - important modulators of nociception and pain behavior, Pain, 98, 1-8 (2002); R. Anwyl, Metabolic glutamate receptors: electrophysiological properties and role in plasticity, Brain Res. Rev., 29, 83-120 (1999).
CAS:
Molecular Formula: C11H14NO5P
HBA: 6
HBD: 4
RotB: 4
PubChemID: 2878
AlogP: -2.114453
TPSA: 130.66
Activity:
Comments:
Last Updated 2008-11-11 02:34 PM
Structure of C-804
About The Program

Since 1959, the NIMH Chemical Synthesis and Drug Supply Program has synthesized and distributed novel research chemicals, psychoactive drugs, and compounds that are unavailable from commercial sources to the scientific community working on research relevant to mental health.

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