NIMH Chemical Synthesis and Drug Supply Program

Compound Information Page

Compound Name: 5-(S)-Cysteinyldopamine
NIMH Code: C-805
Alternative Name:
Indications: May be involved in neural degeneration characteristic of Parkinson's disease; dopamine metabolite
Package Sizes:
References: X.-M. Shen and G. Dryhurst, Influence of glutathione on the oxidation chemistry of 5-S-cysteinyldopamine: potentially neuroprotective reactions of relevance to Parkinson's disease, Tetrahedron, 57, 393-405 (2001); F. Zhang and G. Dryhurst, Reactions of cysteine and cysteinyl derivatives with dopamine-o-quinone and further insoghts into the oxidation chemistry of 5-S-cysteinyldopamine: potential relevance to idiopathic Parkinson's disease, Bioorg. Chem., 23, 193-216 (1995); K. Wakamatsu, S. Ito and T. Nagatsu, Cysteinyldopamine is not incorporated into neuromelanin, Neuroscience Lett., 131, 57-60 (1991).
CAS: 99558-89-1 (base)
Molecular Formula:
HBA: 7
HBD: 5
RotB: 6
PubChemID: 122084
AlogP: -3.65
TPSA: 155.1
Comments: Available as the dihydrochloride salt.
Last Updated 2016-08-31 09:37 AM
Structure of C-805
About The Program

Since 1959, the NIMH Chemical Synthesis and Drug Supply Program has synthesized and distributed novel research chemicals, psychoactive drugs, and compounds that are unavailable from commercial sources to the scientific community working on research relevant to mental health.

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