NIMH Chemical Synthesis and Drug Supply Program

Compound Information Page

NIMH Code: D-509
Compound Name: 5,6-Dihydroxyindole
Alternative Name: 1H-indole-5,6-diol
Abbreviation: Dopamine lutine
PubChemID: 114683
CAS: 3131-52-0
Molecular Formula: C8H7NO2
Biological Activity: Catechol O-methyltransferase (COMT) inhibitor, dopamine metabolite
References: Benigni, J. D.; Minnis, R. L., J. Heterocyclic Chem., 1965, 2, 387-392. Bruning, J.M.; Wang, Y.; Oltrabella, F.; Tian, B.; Kholodar, S.A.; Liu, H.; Bhattacharya, P.; Guo, S.; Holton, J.M.; Fletterick, R.J.; Jacobson, M.P.; England, P.M., Cell Chem. Biol., 2019, 26, 674-685e6.
Last Updated 2021-02-19 08:24 AM
Structure of D-509
About The Program

Since 1959, the NIMH Chemical Synthesis and Drug Supply Program has synthesized and distributed novel research chemicals, psychoactive drugs, and compounds that are unavailable from commercial sources to the scientific community working on research relevant to mental health.

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