NIMH Chemical Synthesis and Drug Supply Program

Compound Information Page

Compound Name: 6-Hydroxydopamine Hydrochloride
NIMH Code: D-502
Alternative Name: 2,4,5-Trihydroxy-beta-phenethylamine Hydrochloride
Indications: Neurotoxin at catecholaminergic terminals
Package Sizes:
References: Y. He, 6-Hydroxydopamine induced apoptosis of dopaminergic cells in the rat substantia nigra, Brain Res., 858, 163-166 (2000); H. Super, Degeneration of Cajal-Retzius cells in the developing cerebral cortex of the mouse after ablation of miningeal cells by 6-hydroxydopamine, Brain Res. Dev. Brain Res., 98, 15-20 (1997).
CAS: 1199-18-4
Molecular Formula: C8H12ClNO3
HBA: 4
HBD: 4
RotB: 2
PubChemID: 4624
AlogP: -.46047133
TPSA: 86.71
Activity: Sympatholytic; Adrenergic Agent
Last Updated 2005-06-21 11:27 AM
Structure of D-502
About The Program

Since 1959, the NIMH Chemical Synthesis and Drug Supply Program has synthesized and distributed novel research chemicals, psychoactive drugs, and compounds that are unavailable from commercial sources to the scientific community working on research relevant to mental health.

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