NIMH Chemical Synthesis and Drug Supply Program

Compound Information Page

Compound Name: Epidepride
NIMH Code: E-703
Alternative Name: (S)-2,3-Dimethoxy-N-[(1-ethyl-2-pyrrolidinyl)methyl]-5-iodobenzamide
Indications: Highly lipophilic dopamine D2 receptor antagonist
Package Sizes:
References: I. M. Skogseid, R. Gerdts, R. Nyberg-Hansen, K. Rootwelt and S. J. Bakke, Usefulness of SPECT and MRI in the diagnosis of atypical parkinsonism, Tidsskr Nor Laegeforen, 121(29), 3399-3403 (2001); K. A. Bergstrom, M. Yu, J. T. Kuikka, K. K. Akerman, J. Hiltunen, J. Lehtonen, C. Halldin and J. Tiihonen, Metabolism of [123I]epidepride may affect brain dopamine D2 receptor imaging with single-photon emission tomography. Eur. J. Nucl. Med., 27(2), 206-208 (2000).
CAS: 107188-87-4
Molecular Formula: C16H23IN2O3
HBA: 4
HBD: 1
RotB: 6
PubChemID: 86101
AlogP: 2.1472
TPSA: 50.8
Activity: Contrast Agent
Last Updated 2005-02-23 04:26 PM
Structure of E-703
About The Program

Since 1959, the NIMH Chemical Synthesis and Drug Supply Program has synthesized and distributed novel research chemicals, psychoactive drugs, and compounds that are unavailable from commercial sources to the scientific community working on research relevant to mental health.

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