NIMH Chemical Synthesis and Drug Supply Program

Compound Information Page

Compound Name: (±)-Fluoxetine Hydrochloride
NIMH Code: F-132
Alternative Name: (±)-N-Methyl-gamma-[4-(trifluoromethyl)phenoxy]benzenepropanamine Hydrochloride
Abbreviation: LY 110140
Indications: serotonin uptake inhibitor; second-generation antidepressive agent
Package Sizes:
References: M. J. O'Neil, Ed., (The) Merck Index, 13th Edition, Monograph 4211, p 741 (2001); D. T. Wong, F. P. Bymaster and E. A. Engleman, Prozac (fluoxetine, lilly 110140), the first selective serotonin uptake inhibitor and an antidepressant drug: twenty years since its first publication, Life Sci., 57 (5), 411-441 (1995).
CAS: 54910-89-3
Molecular Formula: C17H19CIF3NO
HBA: 5
HBD: 1
RotB: 7
PubChemID: 3386
AlogP: 4.1937
TPSA: 21.26
Activity: Serotonin Uptake Inhibitor; Second-Generation Antidepressive Agent
Comments:
Last Updated 2008-11-11 02:43 PM
Structure of F-132
About The Program

Since 1959, the NIMH Chemical Synthesis and Drug Supply Program has synthesized and distributed novel research chemicals, psychoactive drugs, and compounds that are unavailable from commercial sources to the scientific community working on research relevant to mental health.

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