NIMH Chemical Synthesis and Drug Supply Program

Compound Information Page

Compound Name: DL-2-(3,4-Dihydroxybenzyl)-2-hydrazinopropionic Acid
NIMH Code: H-512
Alternative Name: 3-(3,4-dihydroxyphenyl)-2-hydrazinyl-2-methylpropanoic acid
Abbreviation: d,l-Carbidopa
Indications: Aromatic-l-amino-acid decarboxylase inhibitor, used in Parkinson's Disease to reduce peripheral adverse effects of Levodopa
Package Sizes:
References: Sletzinger, M.; Chemerda, J. M.; Bollinger, F. W., J. Med. Chem., 1963, 6, 101-103. Gilbert, J.A.; Frederick, L.M.; Ames, M.M., Clin, Cancer Res, 2000, 6, 4365–4372.
CAS: 302-53-4
Molecular Formula: C10H14N2O4
HBA: 6
HBD: 5
RotB: 4
PubChemID: 2563
AlogP: -1.726216
TPSA: 115.81
Activity: Aromatic-l-amino-acid decarboxylase inhibitor
Last Updated 2021-02-23 03:58 PM
Structure of H-512
About The Program

Since 1959, the NIMH Chemical Synthesis and Drug Supply Program has synthesized and distributed novel research chemicals, psychoactive drugs, and compounds that are unavailable from commercial sources to the scientific community working on research relevant to mental health.

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