NIMH Chemical Synthesis and Drug Supply Program

Compound Information Page

NIMH Code: H-512
Compound Name: DL-2-(3,4-Dihydroxybenzyl)-2-hydrazinopropionic Acid
Alternative Name: 3-(3,4-dihydroxyphenyl)-2-hydrazinyl-2-methylpropanoic acid
Abbreviation: d,l-Carbidopa
PubChemID: 2563
CAS: 302-53-4
Molecular Formula: C10H14N2O4
Biological Activity: Aromatic-l-amino-acid decarboxylase inhibitor, used in Parkinson's Disease to reduce peripheral adverse effects of Levodopa
References: Sletzinger, M.; Chemerda, J. M.; Bollinger, F. W., J. Med. Chem., 1963, 6, 101-103. Gilbert, J.A.; Frederick, L.M.; Ames, M.M., Clin, Cancer Res, 2000, 6, 4365–4372.
Last Updated 2021-02-23 03:58 PM
Structure of H-512
About The Program

Since 1959, the NIMH Chemical Synthesis and Drug Supply Program has synthesized and distributed novel research chemicals, psychoactive drugs, and compounds that are unavailable from commercial sources to the scientific community working on research relevant to mental health.

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