NIMH Chemical Synthesis and Drug Supply Program

Compound Information Page

Compound Name: (±)-7-Hydroxy-DPAT Hydrobromide
NIMH Code: H-701
Alternative Name: (±)-7-Hydroxy-2-(di-n-propylamino)tetralin Hydrobromide
Indications: selective D3 dopamine agonist
Package Sizes:
References: D. Levesque, J. Diaz, C. Pilon, M.-P. Martres, B. Giros, E. Souil, D. Schott, J.-L. Morgat, J.-C. Schwartz and P. Sokoloff, Identification, characterization, and localization of the dopamine D3 receptor in rat brain using 7-[3H]hydroxy-N,N-di-n-propyl-2-aminotetralin, Proc. Natl. Acad. Sci. USA, 89, 8155-8159 (1992); T. B. Mulder, J. B. De Vries, D. Dijkstra, J. W. Wiechers, C. J. Grol and A. S. Horn, Further in vivo and in vitro studies with the putative presynaptic dopamine agonist N,N-dipropyl-7-hydroxy-2-aminotetralin, Naunyn Schmiedeberg's Arch. Pharmacol., 494-501 (1987).
CAS: 74938-11-7
Molecular Formula: C16H26BrNO
HBA: 2
HBD: 1
RotB: 5
PubChemID: 1219
AlogP: 3.0038974
TPSA: 23.47
Activity: Dopamine Agonist
Last Updated 2008-11-11 02:47 PM
Structure of H-701
About The Program

Since 1959, the NIMH Chemical Synthesis and Drug Supply Program has synthesized and distributed novel research chemicals, psychoactive drugs, and compounds that are unavailable from commercial sources to the scientific community working on research relevant to mental health.

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