NIMH Chemical Synthesis and Drug Supply Program

Compound Information Page

Compound Name: 2-(3-Amino-4-iodophenoxy)methylimidazoline dihydrochloride
NIMH Code: I-707
Alternative Name:
Abbreviation: AMIPI
Indications: Imidazoline-guaninidine binding site (IGRS) ligand, PET tracer precursor
Package Sizes:
References: Raddatz, R.; Parini, A.; Lanier, S. M., Mol. Pharmacol., 1997, 52, 549-553. Ivkovic, B.; Bakthavachalam, V.; Zhang, W.; Parini, A.; Diz, D.; Bosch, S.; Neumeyer, J. L.; Lanier, S. M., Mol. Pharmacol., 1994, 46, 15-23.
CAS: 157616-43-8
Molecular Formula: C10H14Cl2IN3O
HBA: 4
HBD: 2
RotB: 3
PubChemID:
AlogP: 1.4983
TPSA: 59.64
Activity: Imidazoline-guaninidine binding site (IGRS) ligand, PET tracer precursor
Comments: CAS Number is for the 125I-labeled analog
Last Updated 2021-02-24 09:43 AM
Structure of I-707
About The Program

Since 1959, the NIMH Chemical Synthesis and Drug Supply Program has synthesized and distributed novel research chemicals, psychoactive drugs, and compounds that are unavailable from commercial sources to the scientific community working on research relevant to mental health.

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