NIMH Chemical Synthesis and Drug Supply Program

Compound Information Page

Compound Name: 2-Hydroxyimipramine
NIMH Code: I-503
Alternative Name:
Abbreviation:
Indications:
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References: R. T. Coutts, P. Su, G. B. Baker and M. Daneshtalab, Metabolism of imipramine in vitro by isoenzyme CYP2D6 expressed in a human cell line, and observations on metabolic stability, J. Chromatography, Biomed. Applications, 615, 265-272 (1993); T. B. Zeugin, K. Brosen and U. A. Meyer, Determination of imipramine and seven of its metabolites in human liver microsomes by a high-performance liquid chromatographic method, Anal. Biochem., 189, 99-102 (1990); J. I. Javaid, J. M. Perel and J. M. Davis, Inhibition of biogenic amines uptake by imipramine, desipramine, 2 OH-imipramine and 2 OH-desipramine in rat brain, Life Sci., 24, 21-28 (1979).
CAS: 303-70-8
Molecular Formula: C19H24N2O
HBA: 3
HBD: 1
RotB: 4
PubChemID: 108051
AlogP: 3.541388
TPSA: 26.71
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Comments:
Last Updated 2006-08-09 11:19 AM
Structure of I-503
About The Program

Since 1959, the NIMH Chemical Synthesis and Drug Supply Program has synthesized and distributed novel research chemicals, psychoactive drugs, and compounds that are unavailable from commercial sources to the scientific community working on research relevant to mental health.

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