NIMH Chemical Synthesis and Drug Supply Program

Compound Information Page

Compound Name: 1,2,3,4-Tetrahydroisoquinoline Hydrochloride
NIMH Code: I-702
Alternative Name:
Abbreviation: TIQ
Indications: Potential dopaminergic neurotoxin
Package Sizes:
References: E. Lorenc-Koci, K. Golembiowska and J. Wardas, 1,2,3,4-Tetrahydroisoquinoline protects terminals of dopaminergic neurons in the striatum against the malonate-induced neurotoxicity, Brain. Res., 1051, 145-154 (2005); E. Lorenc-Koci, J. Wojcikowski, M. Kot, A. Haduch, J. Boksa and W. A. Daniel, Disposition of 1,2,3,4-tetrahydroisoquinoline in the brain of male Wistar and Dark Agouti rats, Brain Res., 996, 168-179 (2004); T. Nagatsu, Isoquinoline neurotoxins in the brain and Parkinson's disease, Neuroscience Res., 29, 99-111 (1997).
CAS: 91-21-4
Molecular Formula: C9H12ClN
HBA: 1
HBD: 1
RotB: 0
PubChemID: 7046
AlogP: 1.5538
TPSA: 12.03
Activity:
Comments:
Last Updated 2006-08-11 12:19 PM
Structure of I-702
About The Program

Since 1959, the NIMH Chemical Synthesis and Drug Supply Program has synthesized and distributed novel research chemicals, psychoactive drugs, and compounds that are unavailable from commercial sources to the scientific community working on research relevant to mental health.

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