NIMH Chemical Synthesis and Drug Supply Program

Compound Information Page

Compound Name: (2S,3S,4S)-2-Methyl-2-(carboxycyclopropyl)glycine
NIMH Code: M-804
Alternative Name:
Abbreviation: MCCG
Indications: Group II metabotropic glutamate receptor antagonist
Package Sizes:
References: T. Knopel, S. Lukie, T. Leonardt, P. J. Flor, R. Kuhn and F. Gasparini, Pharmacological characterization of MCCG and MAP4 at the mGluR1b, mGluR2 and mGLUR4a human metabotropic glutamate receptor subtypes, Neuropharmacol., 34, 1099-1102 (1995); H. Pajouhesh, K. Curry, H. Pajouhesh, M. H. Meresht and B. Patrick, Stereospecific synthesis and absolute configuration of the (2S,3S,4S)-isomer of 2-methyl-2-(carboxycyclopropoyl)glycine (MCCG), Tetrahedron: Asym., 14, 593-596 (2003).
CAS: 157381-42-5
Molecular Formula: C7H11NO4
HBA: 5
HBD: 3
RotB: 3
PubChemID: 6536817
AlogP: -2.983777
TPSA: 100.62
Last Updated 2006-08-14 02:06 PM
Structure of M-804
About The Program

Since 1959, the NIMH Chemical Synthesis and Drug Supply Program has synthesized and distributed novel research chemicals, psychoactive drugs, and compounds that are unavailable from commercial sources to the scientific community working on research relevant to mental health.

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