NIMH Chemical Synthesis and Drug Supply Program

Compound Information Page

Compound Name: (+)-McN-5652
NIMH Code: M-707
Alternative Name: (6S,10bR)-(+)-cis-1,2,3,5,6,10b-Hexahydro-6-[(4-methylthio)phenyl]pyrrolo[2,1-a]isoquinoline
Abbreviation: (6S,10bR)-6-(4-methylsulfanylphenyl)-1,2,3,5,6,10b-hexahydropyrrolo[2,1-a]isoquinoline
Indications: Serotonin transporter inhibitor (active enantiomer)
Package Sizes:
References: Maryanoff, B. E.; McComsey, D. F.; Gardocki, J. F.; Shank, R. P., Costanzo, M. J.; Nortey, S. O.; Schneider, C. R.; Setler, P. E., J. Med. Chem., 1987, 30, 1433-1454. Smith, D. F.; Jensen, P. N.; Poulsen, S. H.; Mikkelsen, E. O.; Elbaz, E.; Glaser, R., Eur. J. Pharmacol., 1991, 196, 85-92.
CAS: 103729-16-4
Molecular Formula: C19H22ClNO4S
HBA: 2
HBD: 0
RotB: 2
PubChemID: 3036461
AlogP: 4.5867
TPSA: 28.54
Activity: Serotonin transporter inhibitor (active enantiomer)
Comments:
Last Updated 2021-03-01 03:24 PM
Structure of M-707
About The Program

Since 1959, the NIMH Chemical Synthesis and Drug Supply Program has synthesized and distributed novel research chemicals, psychoactive drugs, and compounds that are unavailable from commercial sources to the scientific community working on research relevant to mental health.

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