NIMH Code: | M-708 |
Compound Name: | (-)-McN-5652 |
Alternative Name: | (6R,10bS)-(-)-cis-1,2,3,5,6,10b-Hexahydro-6-[(4-methylthio)phenyl]pyrrolo[2,1-a]isoquinoline Perchorate |
Abbreviation: | (-)-McN-5652 |
PubChemID: | 6336338 |
CAS: | 96795-89-0 |
Molecular Formula: | C19H22ClNO4S |
Biological Activity: | Serotonin transporter inhibitor (inactive enantiomer) |
References: | B. E. Maryanoff, D. F. McComsey, J. F. Gardocki, R. P. Shank, M. J. Costanzo, S. O. Nortey, C. R. Schneider and P. E. Setler, Pyrroloisoquinoline antidepressants. 2. In-depth exploration of structure-activity relationships, J. Med. Chem., 30, 1433-1454 (1987); D. F. Smith, P. N. Maryanoff, B. E.; McComsey, D. F.; Gardocki, J. F.; Shank, R. P., Costanzo, M. J.; Nortey, S. O.; Schneider, C. R.; Setler, P. E., J. Med. Chem., 1987, 30, 1433-1454. Smith, D. F.; Jensen, P. N.; Poulsen, S. H.; Mikkelsen, E. O.; Elbaz, E.; Glaser, R., Eur. J. Pharmacol., 1991, 196, 85-92. |
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Last Updated 2021-03-01 03:26 PM |
Since 1959, the NIMH Chemical Synthesis and Drug Supply Program has synthesized and distributed novel research chemicals, psychoactive drugs, and compounds that are unavailable from commercial sources to the scientific community working on research relevant to mental health.