NIMH Chemical Synthesis and Drug Supply Program

Compound Information Page

Compound Name: (+)-MK-801 hydrogen maleate
NIMH Code: M-107
Alternative Name: (Z)-but-2-enedioic acid;(1S,9R)-1-methyl-16-azatetracyclo[7.6.1.02,7.010,15]hexadeca-2,4,6,10,12,14-hexaene hydrogen maleate; (5R,10S)-(+)-5-Methyl-10,11-dihydro-5H-dibenzo[a,d]cycloheptene-5,10-imine hydrogen maleate
Abbreviation: Dizocilpine hydrogen maleate
Indications: Selective, non-competitive NMDA glutamate receptor antagonist
Package Sizes:
References: Griesbach, G. S.; Amsel, A., Proc. Natl. Acad. Sci. USA, 1998, 95, 11435-11439. Wong, E. H. F.; Kemp, J. A.; Priestley, T.; Knight, A. R.; Woodruff, G. N.; Iversen, L. L., Proc. Natl. Acad. Sci., 1986, 83, 7104-7108.
CAS: 77086-22-7
Molecular Formula: C20H19NO4
HBA: 5
HBD: 3
RotB: 2
PubChemID: 6420042
AlogP: 3.2987
TPSA: 86.6
Activity: Selective, non-competitive NMDA glutamate receptor antagonist
Comments:
Last Updated 2021-03-01 09:11 AM
Structure of M-107
About The Program

Since 1959, the NIMH Chemical Synthesis and Drug Supply Program has synthesized and distributed novel research chemicals, psychoactive drugs, and compounds that are unavailable from commercial sources to the scientific community working on research relevant to mental health.

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