NIMH Chemical Synthesis and Drug Supply Program

Compound Information Page

NIMH Code: M-107
Compound Name: (+)-MK-801 hydrogen maleate
Alternative Name: (Z)-but-2-enedioic acid;(1S,9R)-1-methyl-16-azatetracyclo[,7.010,15]hexadeca-2,4,6,10,12,14-hexaene hydrogen maleate; (5R,10S)-(+)-5-Methyl-10,11-dihydro-5H-dibenzo[a,d]cycloheptene-5,10-imine hydrogen maleate
Abbreviation: Dizocilpine hydrogen maleate
PubChemID: 6420042
CAS: 77086-22-7
Molecular Formula: C20H19NO4
Biological Activity: Selective, non-competitive NMDA glutamate receptor antagonist
References: Griesbach, G. S.; Amsel, A., Proc. Natl. Acad. Sci. USA, 1998, 95, 11435-11439. Wong, E. H. F.; Kemp, J. A.; Priestley, T.; Knight, A. R.; Woodruff, G. N.; Iversen, L. L., Proc. Natl. Acad. Sci., 1986, 83, 7104-7108.
Last Updated 2021-03-01 09:11 AM
Structure of M-107
About The Program

Since 1959, the NIMH Chemical Synthesis and Drug Supply Program has synthesized and distributed novel research chemicals, psychoactive drugs, and compounds that are unavailable from commercial sources to the scientific community working on research relevant to mental health.

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