NIMH Chemical Synthesis and Drug Supply Program

Compound Information Page

Compound Name: (-)-3-Iodo-MK-801 hydrochloride
NIMH Code: M-141
Alternative Name: 4-iodo-1-methyl-16-azatetracyclo[7.6.1.02,7.010,15]hexadeca-2(7),3,5,10,12,14-hexaene hydrochloride
Abbreviation: 3-Iododizocilpine
Indications: NMDA antagonist MK-801 analog
Package Sizes:
References: Yang, D.J.; Ciliax, B.J.; Van Dort, M.E.; Gildersleeve, D.L.; Pirat, J.L.; Young, A.B.; Wieland, D.M., Pharm. Res., 1989, 6, 474-476. Ransom, R.W.; Eng, W.S.; Burns, H.D.; Gibson, R.E.; Solomon, H.F., Life Sci., 1990, 46, 1103-1110.
CAS: 119508-63-3
Molecular Formula: C16H15ClIN
HBA: 1
HBD: 1
RotB: 0
PubChemID: 195311
AlogP: 4.2893
TPSA: 12.03
Activity: NMDA antagonist MK-801 analog
Comments: CAS Number and Pubchem ID are for the 125I-labeled analog
Last Updated 2021-03-01 09:18 AM
Structure of M-141
About The Program

Since 1959, the NIMH Chemical Synthesis and Drug Supply Program has synthesized and distributed novel research chemicals, psychoactive drugs, and compounds that are unavailable from commercial sources to the scientific community working on research relevant to mental health.

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