NIMH Chemical Synthesis and Drug Supply Program

Compound Information Page

Compound Name: (+)-3-Trimethylsilyl-MK-801 hydrochloride
NIMH Code: M-145
Alternative Name:
Indications: Radioiodinated (+)-3-iodo-MK-801 precursor
Package Sizes:
References: R. W. Ransom, W. Eng, H. D. Burns, R. E. Gibson and H. F. Solomon, (+)-3-[123I]Iodo-MK-801: synthesis and characterization of binding to the N-methyl-D-aspartate receptor complex, Life. Sci., 46, 1103-1110 (1990).
Molecular Formula: C19H24ClNSi
HBA: 1
HBD: 1
RotB: 1
AlogP: 4.8833
TPSA: 12.03
Activity: Radioiodinated (+)-3-iodo-MK-801 precursor
Last Updated 2021-03-01 09:25 AM
Structure of M-145
About The Program

Since 1959, the NIMH Chemical Synthesis and Drug Supply Program has synthesized and distributed novel research chemicals, psychoactive drugs, and compounds that are unavailable from commercial sources to the scientific community working on research relevant to mental health.

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