NIMH Chemical Synthesis and Drug Supply Program

Compound Information Page

Compound Name: Mifepristone
NIMH Code: M-703
Alternative Name: (11-beta,17-beta)-11-[4-(Dimethylamino)phenyl]-17-hydroxy-17-(1-propynyl)estra-4,9-dien-3-one
Abbreviation: RU-486
Indications: Progesterone receptor antagonist; stimulates prolactin secretion
Package Sizes:
References: M. J. O'Neil, Ed., (The) Merck Index, 13th Edition, Monograph 6209, p 1103 (2001).
CAS: 84371-65-3
Molecular Formula: C29H35NO2
HBA: 3
HBD: 1
RotB: 3
PubChemID: 6712024
AlogP: 4.9
TPSA: 40.54
Activity: Abortifacient Agent, Steroidal Contraceptive; Hormone Antagonist; Luteolytic Age
Last Updated 2006-03-23 10:12 AM
Structure of M-703
About The Program

Since 1959, the NIMH Chemical Synthesis and Drug Supply Program has synthesized and distributed novel research chemicals, psychoactive drugs, and compounds that are unavailable from commercial sources to the scientific community working on research relevant to mental health.

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