NIMH Chemical Synthesis and Drug Supply Program

Compound Information Page

Compound Name: (±)-4-Phenyl-2-(propioamido)tetralin
NIMH Code: P-801
Alternative Name:
Abbreviation: 4P-PDOT
Indications: melatonin receptor antagonist
Package Sizes:
References: A. S. Horn and M. L. Dubocovich, US Patent 5,151,446 (September 29, 1992); C. Ersahin, M. L. Masana and M. L. Dubocovich, Constitutively active melatonin MT1 receptors in male rat caudel arteries, Eur. J. Pharmacol., 439, 171-172 (2002); M. A. Rivera-Bermudez, M. I. Masana, G. M. Brown, D. J. Earnest and M. L. Dubocovich, Immortalized cells from the rat suprachiasmatic nucleus express functional melatonin receptors, Brain Res., 1002, 21-27 (2004).
CAS:
Molecular Formula: C19H21NO
HBA: 1
HBD: 1
RotB: 3
PubChemID: 3976006
AlogP: 3.8666
TPSA: 29.1
Activity: Melatonin receptor antagonist
Comments:
Last Updated 2008-11-11 02:57 PM
Structure of P-801
About The Program

Since 1959, the NIMH Chemical Synthesis and Drug Supply Program has synthesized and distributed novel research chemicals, psychoactive drugs, and compounds that are unavailable from commercial sources to the scientific community working on research relevant to mental health.

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