NIMH Chemical Synthesis and Drug Supply Program

Compound Information Page

Compound Name: 3-(R)-[2-(S)-(Pyrrolidinylcarbonyl)amino]-2-oxo-1-pyrrolidineacetamide (PAOPA)
NIMH Code: P-803
Alternative Name: 3-(R)-(N-L-Prolylamino)-2-oxo-1-pyrrolidineacetamide
Abbreviation: PAOPA
Indications: MSH release-inhibiting hormone antagonist
Package Sizes:
References: K.-L. Yu, G. Rajakumar, L. K. Srivastava, R. K. Misra and R. L. Johnson, Dopamine receptor modulation by conformationally constrained analogues of Pro-Leu-Gly-NH2, J. Med. Chem., 31, 1430-1436 (1988).
CAS: 106732-52-9
Molecular Formula: C11H18N4O3
HBA: 4
HBD: 3
RotB: 4
PubChemID: 129409
AlogP: -2.8441
TPSA: 104.53
Activity: MSH Release-inhibiting hormone antagonist
Last Updated 2008-11-11 02:57 PM
Structure of P-803
About The Program

Since 1959, the NIMH Chemical Synthesis and Drug Supply Program has synthesized and distributed novel research chemicals, psychoactive drugs, and compounds that are unavailable from commercial sources to the scientific community working on research relevant to mental health.

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