NIMH Chemical Synthesis and Drug Supply Program

Compound Information Page

Compound Name: (±)-Salsolinol Hydrochloride
NIMH Code: S-505
Alternative Name: (±)-6,7-Dihydroxy-1-methyl-1,2,3,4-tetrahydroisoquinoline Hydrochloride
Abbreviation:
Indications: Neurotoxic derivative of dopamine
Package Sizes:
References: L. Antkiewicz-Michaluk, I. Romanska, I. Papla, J. Michaluk, M. Bakalarz, J. Vetulani, A. Krygowska-Wajs and A. Szczudlik, Neurochemical changes induced by acute and chronic administration of 1,2,3,4-tetrahydroisoquinoline and salsolinol in dopaminergic structures of rat brain, Neuroscience, 96, 59-64 (2000); S. Wanpen, P. Govitrapong, S. Shavali, P. Sangchot and M. Ebadi, Salsolinol, a dopamine-derived tetrahydroisoquinoline, induces cell death by causing oxidative stress in dopaminergic SH-SY5Y cells, and the said effect is attenuated by metallothionein, Brain Res., 1005, 67-76 (2004).
CAS: 525-72-4
Molecular Formula: C10H14ClNO2
HBA: 3
HBD: 3
RotB: 0
PubChemID: 54456
AlogP: .65084505
TPSA: 52.49
Activity:
Comments:
Last Updated 2006-05-18 02:56 PM
Structure of S-505
About The Program

Since 1959, the NIMH Chemical Synthesis and Drug Supply Program has synthesized and distributed novel research chemicals, psychoactive drugs, and compounds that are unavailable from commercial sources to the scientific community working on research relevant to mental health.

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