NIMH Chemical Synthesis and Drug Supply Program

Compound Information Page

Compound Name: D-(+)-threo-3-(3,4-Dihydroxyphenyl)serine
NIMH Code: S-501
Alternative Name: (2R,3S)-2-amino-3-(3,4-dihydroxyphenyl)-3-hydroxypropanoic acid
Abbreviation: D-threo-DOPS
Indications: Monoamine oxidase inhibitor
Package Sizes:
References: Hegedus, B.; Krasso, A. F.; Noack, K.; Zeller, P., Helv. Chim. Acta, 1975, 58, 147-162. Bartholini, G.; Constantinidis, J.; Puig, M.; Tissot, R.; Pletscher, A., J. Pharmacol. Exp. Ther., 1975, 193, 525-534.
CAS: 51829-99-3
Molecular Formula: C9H11NO5
HBA: 6
HBD: 5
RotB: 3
PubChemID: 443940
AlogP: -2.6371937
TPSA: 124.01
Activity: Monoamine oxidase inhibitor
Last Updated 2021-04-09 03:25 PM
Structure of S-501
About The Program

Since 1959, the NIMH Chemical Synthesis and Drug Supply Program has synthesized and distributed novel research chemicals, psychoactive drugs, and compounds that are unavailable from commercial sources to the scientific community working on research relevant to mental health.

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