NIMH Code: | S-502 |
Compound Name: | L-(-)-threo-3-(3,4-Dihydroxyphenyl)serine |
Alternative Name: | (2S,3R)-2-amino-3-(3,4-dihydroxyphenyl)-3-hydroxypropanoic acid |
Abbreviation: | Droxidopa; L-DOPS |
PubChemID: | 92974 |
CAS: | 23651-95-8 |
Molecular Formula: | C9H11NO5 |
Biological Activity: | |
References: | Goldstein, D.S., Cardiovas. Drug Rev., 2006, 24, 189-203. Bartholini, G.; Constantinidis, J.; Puig, M.; Tissot, R.; Pletscher, A., J. Pharmacol. Exp. Ther., 1975, 193, 525-534. |
Comments: | Orally available prodrug of norepinephrine used in the treatment of symptomatic orthostatic hypotension due to neurogenic causes of autonomic failure and Parkinson's Disease |
Last Updated 2021-04-09 03:29 PM |
Since 1959, the NIMH Chemical Synthesis and Drug Supply Program has synthesized and distributed novel research chemicals, psychoactive drugs, and compounds that are unavailable from commercial sources to the scientific community working on research relevant to mental health.