NIMH Chemical Synthesis and Drug Supply Program

Compound Information Page

Compound Name: (R)-(+)-SKF-38393 Hydrochloride
NIMH Code: S-101
Alternative Name: (R)-(+)-1-Phenyl-2,3,4,5-tetrahydro-(1H)-3-benzazepine-7,8-diol Hydrochloride
Indications: D1 dopamine receptor agonist; active enantiomer of (±)-SKF-38393
Package Sizes:
References: C. Kaiser, P. A. Dandridge, E. Garvey, R. A. Hahn, H. M. Sarau, P. E. Setler, L. S. Bass and J. Clardy, Absolute stereochemistry and dopaminergic activity of enantiomers of 2,3,4,5-tetrahydro-7,8-dihydroxy-1-phenyl-1H-3-benzazepine, J. Med. Chem., 25, 697-703 (1982).
CAS: 62751-59-1
Molecular Formula: C16H18ClNO2
HBA: 3
HBD: 3
RotB: 1
PubChemID: 6852375
AlogP: 1.4079962
TPSA: 52.49
Last Updated 2008-11-11 11:33 AM
Structure of S-101
About The Program

Since 1959, the NIMH Chemical Synthesis and Drug Supply Program has synthesized and distributed novel research chemicals, psychoactive drugs, and compounds that are unavailable from commercial sources to the scientific community working on research relevant to mental health.

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