NIMH Chemical Synthesis and Drug Supply Program

Compound Information Page

Compound Name: (±)-1-(4'-Aminophenyl)-7-bromo-8-methoxy-3-methyl-2,3,4,5-tetrahydro-(1H)-3-benzazepine
NIMH Code: S-704
Alternative Name: 4'-Amino-8-O-methyl-SKF-83566
Indications: precursor to dopamine D1 receptor alkylating ligand (antagonist)
Package Sizes:
References: V. Bakthavachalam, N. Baindur, B. K. Madras and J. L. Neumeyer, Fluorescent probes for dopamine receptors: synthesis and characterization of fluorescein and 7-nitrobenz-2-oxa-1,3-diazol-4-yl conjugates of D-1 and D-2 receptor ligands, J. Med. Chem., 34, 3235-3241 (1991)
Molecular Formula: C18H21BrN2O
HBA: 3
HBD: 1
RotB: 2
AlogP: 3.5428
TPSA: 38.49
Last Updated 2008-11-11 03:00 PM
Structure of S-704
About The Program

Since 1959, the NIMH Chemical Synthesis and Drug Supply Program has synthesized and distributed novel research chemicals, psychoactive drugs, and compounds that are unavailable from commercial sources to the scientific community working on research relevant to mental health.

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