NIMH Chemical Synthesis and Drug Supply Program

Compound Information Page

NIMH Code: S-705
Compound Name: SR 141716
Alternative Name: N-(Piperidin-1-yl)-5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-1H-pyrazole-3-carboxamide; 5-(4-chlorophenyl)-1-(2,4-dichlorophenyl)-4-methyl-N-piperidin-1-ylpyrazole-3-carboxamide
Abbreviation: Rimonabant
PubChemID: 104850
CAS: 168273-06-1
Molecular Formula: C22H21CI3N4O
Biological Activity: Cannabinoid CB1 receptor inverse agonist used an anorectic anti-obesity drug
References: Beardsley, P. M.; Dance, M. E.; Balster, R. L.; Munzar, P., Eur. J. Pharmacol., 2002, 435, 209-216. DeVries, T. J.; Shaham, Y.; Homberg, J. R.; Crombag, H.; Schurman, K.; Dieben, J.; Vanderschuren, L. J. M. J.; Schoffelmeer, A. N. M., Nat. Med., 2001, 7, 1151-1154.
Comments: Free base
Last Updated 2021-04-09 03:53 PM
Structure of S-705
About The Program

Since 1959, the NIMH Chemical Synthesis and Drug Supply Program has synthesized and distributed novel research chemicals, psychoactive drugs, and compounds that are unavailable from commercial sources to the scientific community working on research relevant to mental health.

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