NIMH Chemical Synthesis and Drug Supply Program

Compound Information Page

NIMH Code: T-802
Compound Name: (+)-alpha-Dihydrotetrabenazine
Alternative Name: (2R,3R,11bR)-9,10-dimethoxy-3-(2-methylpropyl)-2,3,4,6,7,11b-hexahydro-1H-benzo[a]quinolizin-2-ol
Abbreviation: (+)-(2R,3R,11bR)-alpha-Dihydrotetrabenazine
PubChemID: 14580381
CAS: 85081-18-1
Molecular Formula: C19H29NO3
Biological Activity: Active metabolite of tetrabenazine with high affinity for the vesicular monamine transporter (VMAT2)
References: M. R. Kilbourne, L. C. Lee, M. J. Heeg and D. M. Jewett, Chirality, 9, 59-62 (1997). Kilbourne, M.; Lee, L.; Vander Borght, T.; Jewett, D.; Frey, K., Eur. J. Pharmacol., 1995, 278, 249-252.
Comments:
Last Updated 2021-04-12 11:13 AM
Structure of T-802
About The Program

Since 1959, the NIMH Chemical Synthesis and Drug Supply Program has synthesized and distributed novel research chemicals, psychoactive drugs, and compounds that are unavailable from commercial sources to the scientific community working on research relevant to mental health.

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