NIMH Chemical Synthesis and Drug Supply Program

Compound Information Page

Compound Name: 1-[2-(4-Aminophenyl)ethyl]-4-(3-trifluoromethylphenyl)piperazine Dihydrochloride
NIMH Code: T-504
Alternative Name: p-Amino-PE-TFMPP Dihydrochloride
Abbreviation: PAPP, LY 165163
Indications: serotonin agonist
Package Sizes:
References: K. B. Asarch, R. W. Ransom and J. C. Shih, 5-HT-1a and 5-HT-1b selectivity of two phenylpiperazine derivatives: evidence for 5-HT-1b heterogeneity, Life Sci., 36, 1265-1273 (1985); R. W. Ransom, K. B. Asarch and J. C. Shih, [3H]1-[2-(4-Aminophenyl)ethyl]-4-(3-trifluoromethylphenyl)piperazine: a selective radioligand for 5-HT1A receptors in rat brain, J. Neurochem, 46, 68-75 (1986).
CAS: 1814-64-8
Molecular Formula: C19H24Cl2F3N3
HBA: 6
HBD: 1
RotB: 5
PubChemID: 121930
AlogP: 4.2402
TPSA: 32.5
Activity: Serotonin Agonist
Last Updated 2008-11-11 03:03 PM
Structure of T-504
About The Program

Since 1959, the NIMH Chemical Synthesis and Drug Supply Program has synthesized and distributed novel research chemicals, psychoactive drugs, and compounds that are unavailable from commercial sources to the scientific community working on research relevant to mental health.

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