NIMH Chemical Synthesis and Drug Supply Program

Compound Information Page

Compound Name: Tropapride Hydrochloride
NIMH Code: T-704
Alternative Name:
Indications: dopamine D2 receptor antagonist
Package Sizes:
References: J.-F. Rumigny, M. Strolin Benedetti and P. Dostert, Investigation on central dopaminergic receptors (D-2) using the antagonistic properties of new benzamides, J. Pharm. Pharmacol., 36, 373-377 (1984); S. Collin, D. P. Vercauteren, D. Vanderveken, G. Evrard and F. Durant, Structural requirements of Na+-dependent antidopaminergic agents: tropapride, piquindone, zetidoline and metaclopramide. Comparison with Na+-independent ligands, J. Comput. Aided Mol. Des., 3, 39-53 (1989).
CAS: 76352-13-1
Molecular Formula: C23H29ClN2O3
HBA: 4
HBD: 1
RotB: 6
PubChemID: 3065827
AlogP: 2.6583
TPSA: 50.8
Last Updated 2008-11-11 03:04 PM
Structure of T-704
About The Program

Since 1959, the NIMH Chemical Synthesis and Drug Supply Program has synthesized and distributed novel research chemicals, psychoactive drugs, and compounds that are unavailable from commercial sources to the scientific community working on research relevant to mental health.

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