NIMH Chemical Synthesis and Drug Supply Program

Compound Information Page

Compound Name: W-5 [N-(6-Aminocyclohexyl)-1-naphthalenesulfonamide Hydrochloride]
NIMH Code: W-501
Alternative Name:
Abbreviation: W-5
Indications: calmodulin antagonist
Package Sizes:
References: H. Hidaka, M. Asano and T. Tanaka, Structure-activity relationship of calmodulin antagonists: naphthalenesulfonamide derivatives, Mol. Pharmacol., 20, 571-578 (1981); H. Hidaka, Y. Sasaki, T. Tanaka, T. Endo, S. Ohno, Y. Fujii and T. Nagata, N-(6-Aminohexyl)-5-chloro-1-naphthalenesulfonamide, a calmodulin antagonists, inhibits cell proliferation, Proc. Natl. Acad. Sci. USA, 78, 4354-4357 (1981).
CAS: 79458-81-4
Molecular Formula: C16H23ClN2O2S
HBA: 4
HBD: 2
RotB: 7
PubChemID: 4314
AlogP: 1.5534434
TPSA: 80.57
Activity: Vasodilator Agent
Comments:
Last Updated 2008-11-11 03:06 PM
Structure of W-501
About The Program

Since 1959, the NIMH Chemical Synthesis and Drug Supply Program has synthesized and distributed novel research chemicals, psychoactive drugs, and compounds that are unavailable from commercial sources to the scientific community working on research relevant to mental health.

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