NIMH Code: | S-901 |
Compound Name: | Spiperone |
Alternative Name: | (±)-8-[3-(p-Fluorobenzoyl)propyl]-1-phenyl-1,3,8-triazaspiro[4,5]decan-4-one |
Abbreviation: | 8-[4-(4-fluorophenyl)-4-oxobutyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one |
PubChemID: | 5265 |
CAS: | 749-02-0 |
Molecular Formula: | C23H26FN3O2 |
Biological Activity: | Serotonin 5-HT1A, 5-HT2A, 5-HT7, and dopamine D2 antagonist, a typical antipsychotic used to treat schizophrenia |
References: | Zheng, L.T.; Hwang, J.; Ock, J.; Lee, M.G.; Lee, W.H.; Suk, K., J. Neurochem., 2008, 107, 1225–1235. Liang, L.; Macdonald, K.D.; Schwiebert, E.M.; Zeitlin, P.L.; Guggino, W.B., Am J Physiol Cell Physiol., 2008, 296, C131–141. |
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Last Updated 2021-04-12 09:21 AM |
Since 1959, the NIMH Chemical Synthesis and Drug Supply Program has synthesized and distributed novel research chemicals, psychoactive drugs, and compounds that are unavailable from commercial sources to the scientific community working on research relevant to mental health.