NIMH Chemical Synthesis and Drug Supply Program

Compound Information Page

Compound Name: WAY-100635 Maleate
NIMH Code: W-108
Alternative Name: N-[2-[4-(2-Methoxyphenyl)-1-piperazinyl]ethyl]-N-(2-pyridinyl)cyclohexanecarboxamide Maleate
Abbreviation: WAY-100635 Maleate
Indications: serotonin receptor antagonist
Package Sizes:
References: A. Fletcher, E. A. Forster, D. J. Bill, G. Brown, I. A. Cliffe, J. E. Hartley, D. E. Jones. A. McLenachan, K. J. Stanhope, D. J. P. Critchley, K. J. Childs, V. C. Middlefell, L. Lanfumey, R. Corradetti, A.-M. Laporte, H. Gozlan, M. Hamon and C. T. Dourish, Electrophysiological, biochemical, neurohormonal and behavioral studies with WAY-100635, a potent, selective and silent 5-HT1A receptor antagonist, Behav. Brain Res., 73, 337-353 (1995); E. A. Forster, I. A. Cliffe, D. J. Bill, G. M. Dover, D. Jones, Y. Reilly and A. Fletcher, A pharmacological profile of the selective silent 5-HT1A receptor antagonist, WAY-100635, Eur. J. Pharmacol., 281, 81-88 (1995).
CAS: 634908-75-1
Molecular Formula: C29H38N4O6
HBA: 5
HBD: 0
RotB: 7
PubChemID: 11957721
AlogP: 4.086
TPSA: 48.91
Last Updated 2008-11-11 03:06 PM
Structure of W-108
About The Program

Since 1959, the NIMH Chemical Synthesis and Drug Supply Program has synthesized and distributed novel research chemicals, psychoactive drugs, and compounds that are unavailable from commercial sources to the scientific community working on research relevant to mental health.

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