NIMH Chemical Synthesis and Drug Supply Program

Compound Information Page

Compound Name: (±)-Zacopride Hydrochloride
NIMH Code: Z-901
Alternative Name: (±)-4-Amino-N-(1-azabicyclo[2.2.2]oct-3-yl)-5-chloro-2-methoxybenzamide Hydrochloride
Indications: Highly potent 5-HT3 receptor antagonist & 5-HT4 receptor agonist
Package Sizes:
References: R. J. Nayor and B. Naylor, 2-Alkoxy-n-(1-azabicyclo(2.2.2)oct-3-yl)benzamide and thiobenzamide compositions and the use thereof to treat schizophrenia, U.S. Patent No. 4,877,794 (October 31, 1989).
CAS: 90182-92-6
Molecular Formula: C15H21Cl2N3O2
HBA: 5
HBD: 2
RotB: 3
PubChemID: 108182
AlogP: .7189
TPSA: 67.59
Activity: Antiemetic; Serotonin Antagonist
Last Updated 2008-11-11 03:08 PM
Structure of Z-901
About The Program

Since 1959, the NIMH Chemical Synthesis and Drug Supply Program has synthesized and distributed novel research chemicals, psychoactive drugs, and compounds that are unavailable from commercial sources to the scientific community working on research relevant to mental health.

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