NIMH Chemical Synthesis and Drug Supply Program

Compound Information Page

Compound Name: (±)-Zacopride hydrochloride
NIMH Code: Z-901
Alternative Name: 4-Amino-N-(1-azabicyclo[2.2.2]oct-3-yl)-5-chloro-2-methoxybenzamide hydrochloride
Abbreviation:
Indications: Serotonin 5-HT3 receptor antagonist and 5-HT4 receptor agonist, used as antiemetic
Package Sizes:
References: Naylor, R. J.; Naylor, B., 1989, Patent No. US 4,877,794. Smith, W.W.; Sancilio, L.F.; Owera-Atepo, J.B., Naylor, R.J.; Lambert, L., J. Pharm. Pharmacol., 1988, 40, 301-302.
CAS: 101303-98-4
Molecular Formula: C15H21Cl2N3O2
HBA: 4
HBD: 3
RotB: 3
PubChemID: 9928181
AlogP: .7189
TPSA: 67.59
Activity: Serotonin 5-HT3 receptor antagonist and 5-HT4 receptor agonist
Comments:
Last Updated 2021-04-14 08:24 AM
Structure of Z-901
About The Program

Since 1959, the NIMH Chemical Synthesis and Drug Supply Program has synthesized and distributed novel research chemicals, psychoactive drugs, and compounds that are unavailable from commercial sources to the scientific community working on research relevant to mental health.

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